synchrotron
Diameter: 25 metres
cyclotron
Diameter: 7 metres

Presentation of the product, the C400 IONS, and the service

Normandy Hadrontherapy produces the world’s first compact multi-ion system based on a cyclotron. The C400 IONS, developed by Normandy Hadrontherapy, represents the new generation of multi-ion hadrontherapy.

The technological solution proposed by NHa aims to replace the synchrotron with a cyclotron — a much smaller, significantly less expensive piece of equipment that is easier to operate and maintain. Our solution will also have the advantage of accelerating multiple particles and switching from one particle to another much more easily. This will make hadrontherapy more readily accessible to clinical treatment centres.

This choice is made possible notably thanks to IBA’s expertise in this highly specialised field of particle accelerator development. It should be noted that this same technological leap also enabled proton therapy to develop. Some twenty years ago, IBA took the gamble of developing a cyclotron for proton therapy treatment at a time when centres were mainly using large synchrotrons. It was this innovative choice that enabled, on the one hand, the development of proton therapy treatments, and on the other, IBA to position itself as the global market leader.

Technical specifications

The innovative nature of this project lies in developing the first cyclotron capable of accelerating heavy particle beams — up to carbon — suitable for clinical treatments (energy, beam size and intensity). This development is now possible through the combination of cutting-edge technologies (superconductivity, computer simulation programmes, etc.) and techniques developed and proven by IBA (elliptical gap, beam simulation and control, etc.), as well as thanks to IBA’s experience in the field of proton therapy treatment.

Key strengths of cyclotron technology:

Continuous beam

Compact and multi-room layout (1 to 5 rooms)

Simple system

Cost-effective

High beam current

Flash and mini-beams

Easy to maintain

Horizontal and vertical treatment (table and chair)

The innovative nature of the product

It was in 2005 that IBA — the world leader in the sale of proton therapy treatment systems — began investing in the design of a carbon therapy system based on a superconducting isochronous cyclotron.

In the course of the study carried out at the time by IBA, it was decided to involve other scientific and industrial partners. Part of the study was entrusted to a group of accelerator physicists from JINR in Dubna, Russia. The cryogenic coil study was carried out by Sigmaphi, based in Vannes, with support from CERN consultants.

Competitive advantages

NHa’s main innovation consists in developing a multi-particle treatment solution (carbon, helium and proton) based on a cyclotron. This will considerably reduce the investment required for its acquisition by hospital centres. The proposed machine is simpler and more compact.

synchrotron
cyclotron

This change of technology will also simplify its operation and maintenance while offering a significantly broader choice of accelerated particles than what is available today. The treatment solution proposed by NHa will be the most suitable for both treatment centres and research centres.

Our first client CYCLHAD

In Caen, our first centre being equipped with the C400 IONS is taking shape within CYCLHAD, a hadrontherapy treatment and research centre, in partnership with the Centre François Baclesse.

For this centre, we are delivering a multi-particle installation (proton, helium, carbon) comprising three rooms with fixed horizontal beamlines, one of which is dedicated to fundamental physics research.

Cyclhad

  • Proton therapy centre hosting the Baclesse medical teams
  • Future heavy-ion therapy centre
  • International research centre for particle therapy, fundamental physics and industry
  • Hosting of radiobiology offices, laboratories and temporary animal facilities

Progress of the C400 project

Established proactively by local authorities and academic and scientific institutions, the ARCHADE programme brings together healthcare, research and technological innovation in hadrontherapy on a single scientific campus.

The work of the research teams hosted there is facilitated by the immediate accessibility of the laboratories and beams available directly on campus.

2024
Start of installation
Preparation of the CYCLHAD building layout plan
January 2024
Phase 1
Rigging of the lower cyclo section
February 2024
2025
Phase 2
Rigging of the upper cyclo section
July 2025
Phase 3
Cryogenic start-up
December 2025
2026
Phase 4
Magnetic mapping
April 2026
Phase 5
Post-installation mapping
October 2026
2027
Phase 6
Multi-particle beam tests
February 2027
Phase 7
Treatment room installation
June 2027
2028
Delivery
Global testing
February 2028